Crosslinking of the cornea

Author: Dr. Victor Derhartunian 11 September 2024

Crosslinking (CXL) of the cornea uses vitamin B2 (riboflavin) and UV-A radiation to achieve collagen crosslinking – this leads to a hardening of the cornea.

Crosslinking is a new treatment method that has proven to be particularly effective in practice.
Studies and experiments have shown that the cornea can be stiffened by up to 450%.
This effect could be observed after just a few hours.
The success rate of the treatment is 98-99%.

Secure procedure

The complication rate for CXL is less than three percent.
It is a very safe procedure – no serious complications or side effects have been reported to date.

Damage to the deeper layers by the UV-A light is not to be expected.
The riboflavin ensures that the light rays are absorbed.
At the same time, the amount of energy should be set so that damage is excluded.
The expertise of the attending physician is therefore relevant.

Which crosslinking technique is best?There are two CXL procedures

  • EPI-OFF crosslinking – epithelium is removed before the riboflavin is applied
  • EPI-ON Crosslinking – epithelium is only loosened before the riboflavin is applied

Both techniques offer advantages and disadvantages.
You should discuss which one is right for you with your doctor.
Your individual state of health should be taken into account when making the decision.

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Author:

Dr. Victor Derhartunian

Nachdem er sein Handwerk von den beiden Pionieren der Laserchirurgie gelernt hat, gehört Dr. Victor Derhartunian zu den führenden Augenlaser-Chirurgen. Er leitet die Praxis in Wien und kann seine Patienten in fünf Sprachen beraten.